It’s a divisional matchup with massive playoff implications. A loss for the 49ers would all but end their hopes of winning the NFC West, while a win by the Rams would move them closer to the top spot. Have a look on the fresh odds.
Why the Rams Can Win
The Rams put up a season-best 44 points against the Bills but had to hang on to win by just two points. Matthew Stafford found success through the air, especially with his two key weapons, as Puka Nacua and Cooper Kupp combined for 17 receptions, 254 receiving yards, and two touchdowns. Kyren Williams was productive on the ground with 87 yards and two scores. If the Rams can produce at that level against San Francisco, they should cruise to another win.
Back in Week 3, LA squeaked out a 3-point win against the Niners as Joshua Karty made a last-second field goal to give the Rams their first win of the season. Stafford threw for 221 yards and one touchdown in the win, and he did it without Kupp and Nacua, who were both injured. With those players in the lineup, the 49ers' secondary could be busy trying to slow down two of the best receivers in the NFL. LA will also look to take advantage of the 49ers' injury woes, with Christian McCaffrey (CMC) and Jordan Mason already out. They also lost third-string running back Isaac Guerendo, who suffered a foot injury on Sunday.
Why the 49ers Could Win
The 49ers returned to their winning ways with a dominant victory against the Bears. Brock Purdy passed for 325 yards and two touchdowns, Jauan Jennings caught both of those touchdowns, and George Kittle had six receptions for 151 yards. But injuries continue to plague this team, as they are still without standout offensive lineman Trent Williams and defensive end Nick Bosa. In their meeting earlier this season, the 49ers sacked Stafford three times and controlled much of the possession. San Francisco was the better team but lost on a last-second field goal.
Now, the Niners are without many of those key players but still have a shot here. They looked rejuvenated against the Bears, and with a slim chance to make the playoffs, Purdy and company have something to play for. At the very worst, they’d love to play spoilers.
Best Bet Prediction: OVER 49
The Rams have gone over this total in three of their last four games as their offense has been firing on all cylinders. With Purdy healthy, the 49ers' offense looks much different and more potent. They did go over this total in Week 3, and this appears to be another game that should see a lot of points.
Game Betting Odds
- Rams +2.5 (+100)
- 49ers -2.5 (-120)
- Total: 49
- Moneyline: Rams +120, 49ers -142
Recent Betting Trends
- The 49ers are 1-4 ATS in their last five games.
- LA is 7-1 ATS in their last 8 games in December.
- LA is 5-2 ATS in the last 7 games.
- The 49ers are 7-3 ATS in the last 10 vs. LA.
- The Rams are 6-1 SU in their last 7 vs. divisional opponents.