The Kansas City Chiefs (4-0) are set to host the New Orleans Saints (2-2) for a Monday Night Football showdown at GEHA Field at Arrowhead Stadium, kicking off at 8:15 p.m. ET.
Kansas City enters as a solid favorite despite a string of injuries that have taken a toll on their offensive lineup, leaving quarterback Patrick Mahomes and tight end Travis Kelce as key players tasked with maintaining momentum.
Game Lines
Current betting odds at BetOnline.ag:
| Team | Win | Spread | Total |
| New Orleans Saints | +195 | +5.5 (-120) | O43 (-110) |
| Kansas City Chiefs | -235 | -5.5 (EVEN) | U43 (-110) |
The Chiefs
Kansas City’s offense is feeling the impact of several sidelined players, including Isiah Pacheco (fibula), Rashee Rice (knee), and Marquise Brown (shoulder), who are all on injured reserve.
Wide receiver Mecole Hardman (knee) is also questionable, creating a rotating lineup that puts Mahomes in a challenging but familiar position.
Mahomes, known for his adaptable play style and precise passing, ranks 11th in the league with 904 passing yards and is tied for fifth with six touchdowns.
Running back Kareem Hunt has returned to Kansas City and has quickly contributed to the offense, providing solid support in the ground game with 69 rushing yards last week.
Rookie receiver Xavier Worthy brings explosive speed to the field and will be relied upon as an additional deep threat. Worthy has nine receptions for 154 yards and two touchdowns, with three catches for 73 yards and a touchdown in Week 4.
Tight end Travis Kelce remains a focal point for the Chiefs, especially following his seven-catch, 89-yard game against the Chargers in Week 4.
The Saints
The Saints have had an up-and-down season, with an early 2-0 record offset by consecutive close losses. New Orleans relies heavily on running back Alvin Kamara, who’s expected to play despite rib and hip issues.
Kamara ranks among the league’s leaders in rushing yards (362) and touchdowns (5), demonstrating his dual-threat capabilities with a consistent presence in both the run and pass game. Wide receiver Chris Olave, with his precise route-running and separation ability, has recorded 265 receiving yards and a touchdown in 2024.
New Orleans boasts a strong defense, ranking sixth in points allowed per game (17.5) and seventh in rushing yards allowed (96.5), which could challenge a Kansas City offense managing a patchwork lineup.
Despite their defensive strength, the Saints’ offense has slowed, managing only 36 points in the last two games compared to a higher early-season output.
Quarterback Derek Carr, alongside receivers Kamara, Olave, and Rashid Shaheed, is tasked with expanding the offense and finding more reliable options in a heavily targeted core group.
Keys to the Game
For Kansas City, the challenge lies in balancing their offense with limited personnel and maximizing Mahomes and Kelce’s connection, especially with Kareem Hunt back in the lineup to support the ground game. The Chiefs defense, ranked seventh in points allowed, will need to be disciplined in containing Kamara while pressuring Carr into quick decisions.
The Saints, meanwhile, will need to diversify their offensive strategy to overcome a formidable Chiefs defense. Optimizing Carr’s options beyond the usual targets and finding opportunities for explosive plays will be crucial, especially given Kansas City’s defensive prowess.
Final Thoughts
With both teams managing injuries, the outcome may depend on how effectively each offense can adapt and utilize its remaining strengths.
For Kansas City, it’s about sustaining Mahomes’ rhythm; for New Orleans, it’s about keeping their top offensive weapons effective against a resilient Chiefs defense